Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting

Metagenomic next-generation sequencing (mNGS) is an untargeted technique for determination of microbial DNA/RNA sequences in a variety sample types from patients with infectious syndromes. mNGS still its early stages broader translation into clinical applications. To further support the development, implementation, optimization and standardization procedures virus diagnostics, European Society Clinical Virology (ESCV) Network on Next-Generation Sequencing (ENNGS) has been established. The aim ENNGS to bring together professionals involved viral diagnostics share methodologies experiences, develop application guidelines. Following publication Recommendations introduction virology, part I: wet lab procedure this journal, current manuscript aims provide practical recommendations bioinformatic analysis data reporting results clinicians.